Company Overview:

Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.  

Prime Medicine is currently progressing a diversified portfolio of eighteen programs initially focused on genetic diseases with a fast, direct path to treating patients or with a high unmet need because they cannot be treated using other gene-editing approaches. Over time, the Company intends to maximize Prime Editing’s therapeutic potential and advance potentially curative therapeutic options to patients for a broad spectrum of diseases. For more information, please visit www.primemedicine.com.

Co-Op Assignment Overview

Prime Medicine is seeking a co-op for the Spring 2025 semester with experience in animal- and cellular-based studies to join the Lung Biology team. The candidate will be involved in supporting critical efforts in evaluating and identifying delivery candidates for lung-directed dosing in animals towards the development of in vivo gene editing therapies that leverage our cutting-edge Prime Editing technologies. The successful candidate will thrive in a fast-paced research program and will enjoy working with colleagues within and across teams from multi-disciplinary backgrounds.

Primary Responsibilities:

  • Keen interest in learning and performing various animal laboratory techniques
  • Plan and execute in vitro and ex vivo assays to evaluate gene editing activity in relevant cell lines including primary cells and target tissues ex vivo
  • Follow protocols, standard operating procedures, execute assigned tasks and maintain ELN. Share responsibility in lab reagent inventory and maintaining equipment.
  • Work and collaborate cross-functionally with colleagues. Collect, analyze and present data in team meetings.

Required Qualifications:

  • Bachelor/Master candidate in Biology related major
  • Direct experience performing routine laboratory procedures and experiments
  • Hands on experience with sterile techniques and culturing of mammalian cell culture including primary cells
  • Comfortable working with rodent models with preliminary techniques or training on animal studies is a plus

Preferred Qualifications:

  • In-vitro and ex-vivo cell-based assay
  • Gene editing technologies and viral and/or non-viral delivery
  • Animal dosing techniques (IV, Oral, etc)

What We Offer:

  • A cutting-edge team open to mentorship and networking.
  • Full reimbursement for monthly commuting costs including MBTA, Commuter Rail, or Bluebikes, etc.
  • Participation in regular seminars with industry experts.
  • Full participation in employee activities including learning and development offerings, social activities, etc.

NOTE: We are currently not considering co-op candidates outside of the local Boston/Cambridge area.

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.

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