Company Overview

Prime Medicine was founded to bring the promise of gene editing to patients. We use Prime Editing, a next-generation technology that can “search and replace” to restore normal genetic function almost anywhere in the genome. Prime Editing searches to find the precise place in the genome to edit and replaces the segment of faulty DNA with a correct copy of DNA.  A single Prime Editor can correct the individual mutations found across patients, meaning Prime Editing can potentially address more than 90 percent of known disease-causing genetic mutations.  

We envision a world where this technology can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefit to patients.  Prime Medicine offers the opportunity to shape the future of gene editing and transform how medicines are used to treat disease. Realizing the promise of Prime Editing requires a talented team with diversity of viewpoints and expertise. We’re building a group of dedicated, scientifically curious individuals who are passionate about helping patients live longer, healthier lives.

Co-Op Assignment Overview 

Prime Medicine is seeking a co-op for the Fall 2023 semester with experience in cell and molecular biology to join the Ocular team. The candidate will be involved in the group’s effort to conduct studies that apply our prime editing technology to develop a therapy for ocular disease. In this role, the candidate will be responsible for supporting the team through execution of various molecular and cellular biology protocols. In this position, you will receive close mentoring from a top tier scientific team to learn and perform cell and molecular biology techniques.  

We are seeking a candidate who enjoys working within a team and is enthusiastic and curious about applying prime editing technology to treat disease.  

Primary Responsibilities: 

  • Aseptic cell culture  
  • In vivo and iPSC sample processing for downstream analysis 
  • Assist in development of assays for ocular therapeutic discovery 
  • Perform molecular biology assays and techniques, including PCR, qPCR, DNA quantification, etc. 
  • Execute, analyze, and troubleshoot experimental methods and results 
  • Adhere to all laboratory safety requirements and procedures 
  • Maintain thorough and detailed electronic lab notebook and documentation records 
  • Document, summarize, and present data to researchers 


  • B. S. Candidate in Cell Biology, Molecular Biology, Biomedical Engineering, or related major 
  • Basic knowledge of cell biology, molecular biology, and biochemistry  
  • Ability to work safely and independently in R&D lab environment 
  • Strong organization, communication, and interpersonal skills
  • Highly adaptable and ability to effectively work as part of a team 
  • Demonstrated eagerness and ability to quickly learn new techniques 
  • Rigorous and conscientious, exhibiting thoroughness in data interpretation 

Preferred Qualifications: 

  • Familiarity with gene editing, gene therapy, synthetic biology, or biotechnology  
  • Experience in maintaining mammalian cell culture and performing transfections 
  • Experience with molecular biology techniques (DNA/RNA extraction, PCR, cloning, etc.) 
  • Experience with in vivo studies  

What We Offer: 

  • A cutting-edge scientific team open to mentorship and networking 
  • Full reimbursement for monthly commuting costs including subway, commuter rail, parking, Bluebikes, etc. 
  • Participation in regular scientific seminars with industry experts 
  • Full participation in employee activities including learning and development offerings, social activities, etc. 

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.

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