Company Overview

Prime Medicine was founded to bring the promise of gene editing to patients. We use Prime Editing, a next-generation technology that can “search and replace” to restore normal genetic function almost anywhere in the genome. Prime Editing searches to find the precise place in the genome to edit and replaces the segment of faulty DNA with a correct copy of DNA.  A single Prime Editor can correct the individual mutations found across patients, meaning Prime Editing can potentially address more than 90 percent of known disease-causing genetic mutations.  

We envision a world where this technology can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefit to patients.  Prime Medicine offers the opportunity to shape the future of gene editing and transform how medicines are used to treat disease. Realizing the promise of Prime Editing requires a talented team with diversity of viewpoints and expertise. We’re building a group of dedicated, scientifically curious individuals who are passionate about helping patients live longer, healthier lives.

Co-Op Assignment Overview 

Prime Medicine is seeking a co-op for the Fall 2023 semester with desire to gain knowledge and experience in lipid chemistry and cheminformatics to join the lipid Chemistry team. The successful candidate will be involving in novel lipid synthesize, characterization and compound management activities. In this position you will gain comprehensive experience in an innovative lipid nano particles (LNP) discovery process, from designing of lipids to screening. Furthermore, you will use laboratory information management systems (LIMS) to manage prime lipid library. You will be closely working with cross functional teams in pharmacology and formulation.   

Primary Responsibilities: 

  • Assist lipid synthesis and characterization process.   
  • Accurately register novel lipids into LIMS system.  
  • Responsible for storage, retrieval, and distribution of lipids for pharmacology and formulation teams.   
  • Aliquoting samples for LNP screening experiments. 
  • Conduct laboratory work in safe, efficient manner that ensures a safe working environment for colleagues.
  • Support to manage chemical inventory and chemical ordering activities.   


  • B.S. or MS candidate in life sciences or chemical engineering. 
  • Basic knowledge of organic chemistry and analytical chemistry.  
  • Excellent computer skills and troubleshooting skills. 
  • Ability to work independently and within a team. 

Preferred Qualifications: 

  • Understanding of basic organic chemistry, biochemistry, and analytical chemistry.  
  • Aptitude for common computer programs (Excel, Word, and PowerPoint).  
  • Comfortable with learning new software skills.  
  • Familiar with small molecule characterization techniques; TLC, NMR. MS, HPLC.  
  • Exhibit excellent organization, planning and multi-tasking skills.
  • Demonstrates ability to work effectively with cross functional team members.

What We Offer: 

  • A cutting-edge scientific team open to mentorship and networking 
  • Full reimbursement for monthly commuting costs including subway, commuter rail, parking, Bluebikes, etc. 
  • Participation in regular scientific seminars with industry experts 
  • Full participation in employee activities including learning and development offerings, social activities, etc. 

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.

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