Company Overview

Prime Medicine was founded to bring the promise of gene editing to patients. We use Prime Editing, a next-generation technology that can “search and replace” to restore normal genetic function almost anywhere in the genome. Prime Editing searches to find the precise place in the genome to edit and replaces the segment of faulty DNA with a correct copy of DNA.  A single Prime Editor can correct the individual mutations found across patients, meaning Prime Editing can potentially address more than 90 percent of known disease-causing genetic mutations.  

We envision a world where this technology can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefit to patients.  Prime Medicine offers the opportunity to shape the future of gene editing and transform how medicines are used to treat disease. Realizing the promise of Prime Editing requires a talented team with diversity of viewpoints and expertise. We’re building a group of dedicated, scientifically curious individuals who are passionate about helping patients live longer, healthier lives.

Co-Op Assignment Overview:

Prime Medicine is seeking a co-op for the Spring 2023 semester with experience in molecular biology to join the assay development team. The candidate will be involved in research/translational/clinical assay development for different programs. We want curious problem solvers who enjoy working on exciting projects, working within a team and are passionate about developing genetic editing technologies to better human health and well-being.

Primary Responsibilities:

  • Primary responsibilities will include, but are not limited to, molecular cloning, supporting primary cell culture, expansion, transfection, phenotype characterization of gene modified primary human cells and performing assays.
  • Document, present, and communicate experimental data and conclusions in electronic notebook.
  • Collaborate with teammates across assay development and program teams to develop required assays.
  • Adhere to all laboratory safety requirements and procedures, assist in maintaining general laboratory functionality


  • Finishing a BS or MS in Molecular Biology/Cell Biology/Biomedical Science
  • Enthusiastic, quick learner interested in gaining experience in a fast-paced research setting
  • Mammalian cell culture experience and aseptic techniques
  • Experience in experimental design, optimization, and analysis

Preferred Qualifications:

  • Hands on knowledge of ELISA or kit-based assays
  • Experience in molecular biology skills, including PCR, qPCR, cloning and DNA/RNA/Protein isolation
  • Experience collaborating effectively within cross-functional teams
  • Knowledge and/or experience in gene editing

What We Offer:

  • A cutting-edge scientific team dedicated to mentorship and networking
  • Full reimbursement for monthly commuting costs including subway, commuter rail, parking, Bluebikes, etc.
  • Participation in regular scientific seminars with industry experts
  • Full participation in employee activities including learning and development offerings, social activities, etc.

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.

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