team members

Ann Lee

PhD

CTO

Ann Lee, PhD, is the Chief Technical Officer of Prime Medicine. Ann is an accomplished biotech executive with extensive experience and accomplishments in vaccines, biologics, small molecules and cell therapy development and manufacturing. She brings a passion for helping patients, innovating new technologies, and developing employees. Over the course of her career, she has contributed to the licensure and commercialization of 25 new vaccines and medicines, with the most recent being two CAR T cell therapies.

Ann recently worked at BMS, which acquired Celgene and Juno Therapeutics. Ann joined Juno Therapeutics in 2017 as Executive VP of Technical Operations to work in the new field of cell and gene therapy. She built the global Cell Therapy Development and Operations organization responsible for developing new manufacturing processes and technologies, manufacturing, quality assurance, designing new facilities, and creating the global supply chain network and digital systems to deliver these autologous products.

Ann was at Genentech in 2005 as VP of Process R&D and became SVP and Head of Global Technical Development at Roche in 2009. She was responsible for delivering Roche’s global R&D pipeline, as well as tech transfer and technical support for all commercial products. She was a member of corporate strategic portfolio governance committees and worked extensively cross-functionally as well as with external partners across the globe.

Prior to Genentech, Ann joined Merck Research Laboratories, where she advanced through several leadership positions in vaccine development over 14 years. She then became Vice President of Chemical Technology and Engineering in the Manufacturing Division at Merck, overseeing process engineering and technical operations at 10 chemical sites around the world.

Ann is a member of the National Academy of Engineering, a Fellow of the American Academy of Arts and Sciences, and a Fellow of the American Institute of Medical and Biological Engineering. She is the recipient of many scientific and engineering awards and has served on several professional, academic and company boards. She holds a B.S. in chemical engineering from Cornell University, and a Ph.D. in biochemical engineering from Yale University.